Hepatitis E Virus–Associated Meningoencephalitis in a Lung Transplant Recipient Diagnosed by Clinical Metagenomic Sequencing

نویسندگان

  • Jamie A. Murkey
  • Kara W. Chew
  • Margrit Carlson
  • Chelsea L. Shannon
  • Deepika Sirohi
  • Hannah A. Sample
  • Michael R. Wilson
  • Paul Vespa
  • Romney M. Humphries
  • Steve Miller
  • Jeffrey D. Klausner
  • Charles Y. Chiu
چکیده

Hepatitis E virus (HEV) infection uncommonly causes chronic hepatitis and neurologic disease. We describe a case of genotype 3a HEV meningoencephalitis diagnosed by metagenomic next-generation sequencing, illustrating the power of an unbiased molecular approach to microbial testing and the first reported case of HEV infection presumably acquired through lung transplantation.

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عنوان ژورنال:

دوره 4  شماره 

صفحات  -

تاریخ انتشار 2017